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  • Chemical Biology

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    Creative Co-op XC5010 Red Glass Footed Votive Holder 3pc 13.75 , 11.75 & 9.75 H

    Here’s some medicinal chemistry combined with synthetic biology for you. Many people are used to thinking in terms of finding small-molecule probes for various cell targets, and those are valuable things. But what if you want to control a certain population of (for example) ion channels, but there aren’t any compounds that will do the… CRIMSON SPARKLE HURRICANE PILLAR CANDLE-TEALIGHT TREE HOLDER CHRISTMAS PARTYLITE
  • Chemical News

    CROCHET AFGHAN CHUNKY, HANDMADE, 68x68” (173x173 Cm), Shades Of Brown And Beige.

    Georgia Pacific Professional Hardwound Roll Paper Towels 7 x 1000ft White 6 I was interested to see this paper, which goes into detail on a chemical phenomenon that many have seen but no one understands very well: triboluminescence. That word meets with a blank stare or instant recognition; there’s not much in between. It means “emission of light when a material is physically broken”, and that encompasses… CROCHET blanket afghan couch throw wrap chevron ripple handmade baby Christmas
  • Analytical Chemistry

  • Cancer

    Making and Measuring Multivalency

    Here’s an unusual paper that’s studying receptor behavior on cell surfaces by use of atomic force microscopy. (Here’s the SI file, which is free to access). The authors took the marketed VEGF inhibitor vandetanib (VD6474) and attached it through linkers to the AFM tip, and then scanned around the surface of live human umbilical v… Crocheted Afghan Throw - New
  • Drug Assays

    CROSCILL - Blythe bluee & Ivory Multicolor 6 Piece Queen Comforter Set

    Gifts & Decor COPPER MgoldCCAN CANDLE LAMP A common question – well, it should be a common question, anyway – is “How do I make sure that this compound collection is a useful one to screen?” There are alternative forms that come down to the same issues – if you’re putting together a new focused screening set, what should be in it?… Read More
  • Biological News

  • Business and Markets

  • Analytical Chemistry

    A Close Look at Fragments

    Here’s a look from the D. E. Shaw research team at fragment binding, and even if you don’t do fragment-based drug discovery, it’s worth a read. That’s because the mechanisms by which fragments bind to proteins are most likely the fundamental ones by which larger molecules bind as well; this is the reductionist look at… Read More
  • Analytical Chemistry

    A Look at Proteins in Living Cells

    We spend a lot of time in this sort of work thinking about protein structures. Traditionally that’s been the province of X-ray crystallography, later joined by solution NMR, and more latterly by cryo-electron microscopy. Each of these has its own set of advantages and disadvantages, but one big split is between the solid phase (X-ray… CTW Home Collection CTW Lantern Multicolor
  • Academia (vs. Industry)

    Startup Culture, Starting

    Glass Hurricane Candle Holder with Designer Ceramic Base, White and Beige Many readers of this blog work in the biopharma industry, naturally, and of those, many are in and around the (few) locations where a great many of the companies in the industry are born. I myself am in the Boston/Cambridge area, famously thick with companies large and small, and then you have the Bay area… Cuddledown DAISY & POPPY FLORAL BED SKIRT King NEW
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